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Treatment Results of Sinonasal Sarcomas : 20 Cases in Asan Medical Center / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery ; : 579-584, 2009.
Artigo em Coreano | WPRIM | ID: wpr-644879
ABSTRACT
BACKGROUND AND

OBJECTIVES:

Sinonasal sarcomas are relatively rare tumors, accounting for only about 1 percent of all sinonasal malignancies. The purpose of this study is to analyze the clinical features, treatment modalities and outcomes, survival and prognostic factors of sinonasal sarcomas. SUBJECTS AND

METHOD:

We retrospectively reviewed the medical records of 20 patients who were diagnosed and treated for sinonasal sarcomas between July 1993 and June 2006. Potential prognostic factors including age, tumor size, histology and adjuvant treatment were evaluated.

RESULTS:

According to histologic subtype, twenty cases consisted of 7 rhabdomyosarcomas, each 2 cases of spindle cell sarcoma, Ewing's sarcoma, angiosarcoma, and each 1 case of fibrosarcoma, leiomyosarcoma, hemangiopericytoma, peripheral neuroectodermal tumor, myxoid sarcoma, osteosarcoma, chondrosarcoma. The mean follow-up period was 61 months. Fourteen patients (65%) had undergone surgical approach with adjuvant chemotherapy or radiotherapy. Four patients (20%) had undergone surgical treatment only. Two patients (15%) had undergone chemotherapy or radiotherapy. At 5 years, the overall survival rates of sinonasal sarcomas were 65%. The survival rates according to the treatment modality were 100% (surgery only), 66% (surgery with adjuvant chemotherapy or radiotherapy), and 33% (chemotherapy or radiotherapy), respectively. The overall recurrence rates of the sinonasal sarcomas were 25%. The univariate analysis showed that the treatment modality and surgical margin are important prognostic factors for survival.

CONCLUSION:

The 5-year survival rate of sinonasal sarcomas was 65%. Early diagnosis and wide excision with safe resection margin are important for the treatment of sinonasal sarcomas.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Rabdomiossarcoma / Sarcoma / Sarcoma de Ewing / Osteossarcoma / Prontuários Médicos / Taxa de Sobrevida / Estudos Retrospectivos / Seguimentos / Condrossarcoma Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Estudo de rastreamento Limite: Humanos Idioma: Coreano Revista: Korean Journal of Otolaryngology - Head and Neck Surgery Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Rabdomiossarcoma / Sarcoma / Sarcoma de Ewing / Osteossarcoma / Prontuários Médicos / Taxa de Sobrevida / Estudos Retrospectivos / Seguimentos / Condrossarcoma Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Estudo de rastreamento Limite: Humanos Idioma: Coreano Revista: Korean Journal of Otolaryngology - Head and Neck Surgery Ano de publicação: 2009 Tipo de documento: Artigo