Cutaneous Adverse Effects Associated with Iressa(R)(Gefitinib) Medication / 대한피부과학회지
Korean Journal of Dermatology
;
: 92-95, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-64501
ABSTRACT
We report cutaneous adverse effects developed in three patients and are probably related to Iressa(R)(Gefitinib, ZD1839) medication. Iressa(R) is a new anti-cancer agent which acts by inhibiting epidermal growth factor (EGF) receptor signal transduction. The three patients had all taken Iressa(R) for treatment of non-small cell lung cancer and came to our clinic with cutaneous adverse effects. All three patients had acneiform eruptions, and one of the patients also had periungal granulation lesions. Histopathologically, periadnexal inflammatory cellular infiltrations were seen in the acneiform lesions of the three patients and granulation-like tissue proliferations in periungal granulation lesions of the one patient.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transdução de Sinais
/
Erupções Acneiformes
/
Carcinoma Pulmonar de Células não Pequenas
/
Fator de Crescimento Epidérmico
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Ano de publicação:
2005
Tipo de documento:
Artigo
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