Differences in Osteoconduction at Porous Hydroxyapatite according to Pore Geometry / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 643-650, 1999.
Artigo
em Coreano
| WPRIM
| ID: wpr-646283
ABSTRACT
PURPOSE:
To assess the histological response and the reinforcing effects of bone ingrowth within porous hydroxyapatite implants depending on pore geometry. MATERIALS ANDMETHODS:
Three types of porous hydroxyapatite (cylindrical, sponge and cross type) were prepared. Forty-two white rabbits were divided into 3 groups and 5x5x7 mm-sized porous hydroxyapatite block was inserted through the medial cortical window of a proximal tibia. Histomorphological changes were examined using light and scanning electron microscopy. Biomechanical compression test was performed using material test machine.RESULTS:
At four weeks after implantation, the implants showed different histological changes depending on pore geometry. In cylindrical type porous hydroxyapatite, new bone was arranged in a concentric pattern around vessel similar to osteon. In sponge and cross type, irregular lamellar bone pattern was found. At 8 weeks, evidence of remodelling of new bone and bone marrow formation within porous hydroxyapatite was found. In biomechanical study, ultimate compressive strength significantly increased in all three implants after 8 weeks of implantation compared to preimplantation.CONCLUSIONS:
In cylindrical type porous hydroxyapatite, new bone was arranged in a concentric pattern around vessel, and compressive strength was highest. Sponge type porous hydroxyapatite showed irregular lamellar bone pattern and was rather flexible and ductile. Cross type porous hydroxyapatite showed borderline pattern of both cylindrical and sponge type porous hydroxyapatite.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Poríferos
/
Tíbia
/
Medula Óssea
/
Regeneração Óssea
/
Microscopia Eletrônica de Varredura
/
Durapatita
/
Força Compressiva
/
Ósteon
Limite:
Animais
Idioma:
Coreano
Revista:
The Journal of the Korean Orthopaedic Association
Ano de publicação:
1999
Tipo de documento:
Artigo
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