Usefulness of Intraoperative Parathyroid Hormone Assay in Minimally Invasive Surgery / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 426-430, 2009.
Artigo
em Coreano
| WPRIM
| ID: wpr-647135
ABSTRACT
BACKGROUND AND OBJECTIVES:
Intraoperative parathyroid hormone (PTH) assay has been proposed as an effective tool in minimally invasive parathyroidectomy. We evaluated its usefulness during minimally invasive parathyroidectomy. SUBJECTS ANDMETHOD:
Ten patients (female 6, male 4) of primary hyperparathyroidism (8 single diseases, 2 multiple diseases) were analyzed retrospectively. We used computed tomography (CT) and 99mTc-Sestamibi (MIBI) scan for localization of parathyroid lesions preoperatively, and frozen biopsy and PTH assay at 10 (T-10), 20 (T-20) minutes after excision intraoperatively. We also compared the diagnostic sensitivity of CT and MIBI scan and intraoperative PTH.RESULTS:
All patients were treated successfully and in single disease group, diagnostic sensitivity of CT, MIBI scan were 75% and 87.5%, and that of T-10 was 75% and T-20 was 100%. In multiple disease group, diagnostic sensitivity of CT, MIBI scan were 75%, 87.5%, and that of PTH was 80%.CONCLUSION:
Intraoperative PTH assay improves cure rate in minimally invasive parathyroidectomy. It allowed intraoperative recognition of missed parathyroid lesions by preoperative imaging study.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Hormônio Paratireóideo
/
Biópsia
/
Estudos Retrospectivos
/
Paratireoidectomia
/
Tecnécio Tc 99m Sestamibi
/
Hiperparatireoidismo Primário
Tipo de estudo:
Estudo observacional
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Otolaryngology - Head and Neck Surgery
Ano de publicação:
2009
Tipo de documento:
Artigo
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