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Expression of M llerian Inhibiting Substance in Cryptorchidism at the Descending Level of Testis / 대한비뇨기과학회지
Korean Journal of Urology ; : 167-172, 1998.
Artigo em Coreano | WPRIM | ID: wpr-64730
ABSTRACT

PURPOSE:

To investigate the relationship of MIS and cryptorchidism according to the descending level of testis into scrotum, we studied expression degree of MIS by immunohistochemical analysis using anti-human MIS polyclonal antibody in testicular specimen. MATERIALS AND

METHODS:

MIS were stained in excised testis by trauma on each 8 patients as control group and age-matched abdominal, inguinal and prepubic cryptorchidism. The expression were classified as score 1, 2, 3 and 4 according to stained degree of percentage in randomized 16 fields(x400) under the light microscope.

RESULTS:

Of the degree of MIS expression in control group, 87.5% were category 3 or more. The mean score was 3.13+/-0.62. 2. Of the degree of MIS expression in abdominal type cryptorchid testis group that underwent orchiectomies, 68.7% were category 1. The mean score, 1.31 +/- 0.48, showed significant difference compared to control group(p0.05). 4. Of the degree of MIS expression in prepubic type, 75.0% were category 3 or more. And the mean score, 2.88+/-0.62, showed no significant difference compared to control group(p>0.05).

CONCLUSIONS:

Expression of MIS is different according to descending level of testis and may play a role in physiologic changes of testicular descent.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Escroto / Testículo / Orquiectomia / Criptorquidismo Tipo de estudo: Ensaio Clínico Controlado Limite: Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Urology Ano de publicação: 1998 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Escroto / Testículo / Orquiectomia / Criptorquidismo Tipo de estudo: Ensaio Clínico Controlado Limite: Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Urology Ano de publicação: 1998 Tipo de documento: Artigo