Decreased Phenytoin Absorption in Patients with Continuous Enteral Feedings / 대한구급학회지
The Korean Journal of Critical Care Medicine
;
: 102-107, 2000.
Artigo
em Coreano
| WPRIM
| ID: wpr-647524
ABSTRACT
This report supports interactions between phenytoin and both enteral feeding products and nasogastric feeding tube. Five patients in ICU were treated with intravenous phenytoin, which yield detectable therapeutic serum concentrations. After switching to a comparable phenytoin capsule administered by nasogastric feeding tube, their serum phenytoin concentration fell to below assay sensitivity concentrations. Two of them experienced seizures. They were administered by intravenous phenytoin again or another antiepileptic drug, so the seizures were controlled. Some fact of decreased phenytoin absorption in enteral feeding patients is that phenytoin interact enteral feeding product and adhere the nasogastric feeding tube itself. We conclude that it is necessary to use phenytoin with caution in enteral feeding patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenitoína
/
Convulsões
/
Nutrição Enteral
/
Absorção
Limite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Critical Care Medicine
Ano de publicação:
2000
Tipo de documento:
Artigo
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