Tgamadenta in cellular immunity response in vitro to ND-BSA, a semisynthetic antigene of Mycobacterium leprae

ABSTRACT

58 leprosis patients, aged 12-47 years old, treating in the South, were detected cellular immunity response to ultracrushed M. leprae and ND-BSA. Patients had positive response with ND-BSA. Cells having transformed responsed with ND-BSA are lymphocyte and in 5/12 patients there is a participation, mainly of subpopulation of T lymphocyte, there are Tgamadenta cells. When Tgamadenta was removed from cellular mixt, the absorption of H3-Thymidin uncreased dramatically in both ND-BSA nad BSA culture