Re-evaluation of Association between Thrombotic Diasthesis and Legg-Calve-Perthes Disease / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 189-194, 1999.
Artigo
em Coreano
| WPRIM
| ID: wpr-650650
ABSTRACT
Legg-Calve-Perthes disease (LCP) has been reported to be associated with hypofibrinolysis and a deficiency in coagulation. The goal of this prospective study was to confirm or refute these findings and to establish a guide for a screening test. The coagulation systems of twenty-three patients with Legg-Calve-Perthes disease were evaluated by means of the tests which included prothrombin time, activated partial thromboplastin time, antithrombin-III (AT-III), protein C, protein S, lipoprotein(a), and anticardiolipin antibody (ACA). Study subjects were 21 males and 2 females. Mean age was 8.7 years. No abnormal results were found for Antithrombin-III and Protein S, but 2 patients had low Protein C level. Two of 23 patients had Lipoprotein(a) values greater than 30 mg/dl. Another two patients had positive finding for Anticardiolipin antibody. There were no statistical differences in all parameters between Catterall group stage in the patients with Legg-Calve-Perthes disease. We were unable to establish an association between thrombotic tendency and Legg-Calve-Perthes disease based on this prospective study. So, routine screening of patients with Legg-Calve-Perthes disease for abnormalities of antithrombotic factors would be not warranted.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tempo de Tromboplastina Parcial
/
Tempo de Protrombina
/
Proteína C
/
Programas de Rastreamento
/
Estudos Prospectivos
/
Proteína S
/
Lipoproteína(a)
/
Anticorpos Anticardiolipina
/
Doença de Legg-Calve-Perthes
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Journal of the Korean Orthopaedic Association
Ano de publicação:
1999
Tipo de documento:
Artigo
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