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Contrast-enhanced ultrasound analysis of renal perfusion in normal micropigs
Journal of Veterinary Science ; : 311-314, 2012.
Artigo em Inglês | WPRIM | ID: wpr-65161
ABSTRACT
Contrast-enhanced ultrasound is one of method for evaluating renal perfusion. The purpose of this project was to assess perfusion patterns and dynamics in normal micropig kidney using ultrasonographic contrast media. Eight young healthy micropigs were included in this study. Micropigs were anesthetized with propofol and received an intravenous bolus of microbubble contrast media through an ear vein. Time/mean pixel value (MPV) curves were generated for selected regions in the right renal cortex and medulla. The parenchyma was enhanced in two phases. The cortex was first enhanced followed by a more gradual enhancement of the medulla. A significant difference in perfusion was detected between the cortex and medulla. Following the bolus injection, the average upslope was 0.68 +/- 0.27 MPV/sec, downslope was -0.27 +/- 0.13 MPV/sec, baseline was 73.9 +/- 16.5 MPV, peak was 84.6 +/- 17.2 MPV, and time-to-peak (from injection) was 17.5 +/- 6.6 sec for the cortex. For the medulla, the average upslope was 0.50 +/- 0.24 MPV/sec, downslope was -0.12 +/- 0.06 MPV/sec, baseline was 52.7 +/- 7.0 MPV, peak was 65.2 +/- 9.3 MPV, and time-to-peak (from injection) was 27.5 +/- 5.0 sec. These data can be used as normal reference values for studying young micropigs.
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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Valores de Referência / Circulação Renal / Hexafluoreto de Enxofre / Suínos / Porco Miniatura / Processamento de Imagem Assistida por Computador / Modelos Lineares / Ultrassonografia / Meios de Contraste / Microbolhas Tipo de estudo: Estudo diagnóstico Limite: Animais Idioma: Inglês Revista: Journal of Veterinary Science Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Valores de Referência / Circulação Renal / Hexafluoreto de Enxofre / Suínos / Porco Miniatura / Processamento de Imagem Assistida por Computador / Modelos Lineares / Ultrassonografia / Meios de Contraste / Microbolhas Tipo de estudo: Estudo diagnóstico Limite: Animais Idioma: Inglês Revista: Journal of Veterinary Science Ano de publicação: 2012 Tipo de documento: Artigo