A Case of NK/T Cell Lymphoma in Sinonasal Tract / 대한이비인후과학회지

ABSTRACT

Primary sinonasal NK/T cell lymphoma is relatively common in Asia than in Western countries, comprising up to 7% of all Non-Hodgkin's lymphoma with a marked preponderance demonstrating a NK/T-cell phenotype. Sinonasal NK/T cell lymphoma is typically associated with abundant crust on mucosal surface, widespread necrosis, and extensive inflammation. Sinonasal NK/T cell lymphoma is characterized by a progressive clinical course and poor prognosis, and histologically, it shows angioinvasion and necrosis. It is referred to by such terms as non-healing granuloma, lethal granuloma or midline granuloma. Treatment of NK/T cell lymphoma consists of radiotherapy, chemotherapy, or both. We experienced a case of sinonasal NK/T cell lymphoma in a 65 year old man who complained of periorbital swelling.