Study on CNS Oxytocinergic Pathway Projecting to the Mammary Nerve of the Rat / 대한해부학회지
Korean Journal of Anatomy
;
: 705-712, 1997.
Artigo
em Coreano
| WPRIM
| ID: wpr-652239
ABSTRACT
To identify the central innervating the mammary nerve, viral retrograde transneuronal labelling methods were employed. Pseudorabies virus 6 microliter was injected into the mammary nerve of adult female Sprague-Dawley rats. After 4 days of survival, the animals were perfused with 4% paraformaldehyde-lysine periodate and their brains were processed for immunohistochemistry and double immunofluorescent staining of Pseudorabies virus or oxytocin using polyclonal antibodies. Several nuclei in brain were retrogradely labelled with Pesudorabies virus.Only a few magnocellular neurons of the paraventricular nucleus throughout whole brain showed double immunoreactivity to Pseudorabies virus and oxytocin. Approximately 11 percent of the oxytocinergic cells of the paraventricular nucleus,especially in three subnuclei[dorsomedial cap, lateral magnocelluar part and ventral part] showed double positive reaction to both Pseudorabies virus and oxytocin. These data demonstrate that some CNS cells projecting to the mammary nerve contained oxytocin and it may acts as a neurotransmitter in this pathway and a hormone targeting milk production and secretion.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Núcleo Hipotalâmico Paraventricular
/
Pseudorraiva
/
Encéfalo
/
Ocitocina
/
Imuno-Histoquímica
/
Ratos Sprague-Dawley
/
Herpesvirus Suídeo 1
/
Neurotransmissores
/
Leite
/
Anticorpos
Limite:
Animais
/
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Anatomy
Ano de publicação:
1997
Tipo de documento:
Artigo
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