Rosai-Dorfman Disease of the Nasal Cavity and Nasopharynx / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
;
: 570-573, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-652934
ABSTRACT
Rosai-Dorfman disease is a rare disorder of unknown etiology and is usually associated with benign proliferation of hematopoietic and fibrous tissue that often manifests in the head and neck region. The most common clinical presentation of this entity is bilateral, nontender cervical lymphadenopathy, but an extranodal form of the disease may develop in up to 43% of patients. We report a case of extranodal Rosai-Dorfman disease occurring in the nasal cavity and the nasopharynx. A 25-year-old male visited the clinic with a complaint of nasal obstruction for several months. Mass originating from anterior portion of septum and nasopharyngeal cavity was observed by endoscopy. Endoscopic guided incisional biopsy of the lesion was performed. The histopathologic findings revealed clusters of large, foamy histiocytes with abundant clear cytoplasm, lymphophagocytosis, and heavy infiltration of lymphocytes and plasma cells, which are the key features of Rosai-Dorfman disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Plasmócitos
/
Biópsia
/
Linfócitos
/
Histiocitose Sinusal
/
Obstrução Nasal
/
Nasofaringe
/
Citoplasma
/
Endoscopia
/
Cabeça
/
Histiócitos
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Otolaryngology - Head and Neck Surgery
Ano de publicação:
2008
Tipo de documento:
Artigo
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