Comparison of CRP in Spinal Compression Fractures: Simple vs Malignant metastatic disease / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 129-132, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-654985
ABSTRACT
PURPOSE:
We undertook to evaluate the efficacy of C-reactive protein (CRP) determination as a screening test for the detection of malig-nancy in compression fracture patients by comparing simple compression fractures and malignant metastatic compression fractures of spine. MATERIALS ANDMETHODS:
From January 1998 to March 2001, fifty-one patients who had compression fracture of spine with chronic back pain were analysed for CRP levels. The thirty-six patients had simple compression fractures of the spine and fifteen patients malignant metastatic compression fractures. The sensitivity, specificity and positive predictive value of CRP in the screening of benign simple compression fractures were calculated.RESULTS:
CRP levels in malignant metastatic compression fracture were significantly higher than in simple compression fracture. The sensitivity of CRP in simple compression fractures was 97%, its specificity 80% and its positive predictive value 92%.CONCLUSION:
We consider CRP titer to be a useful screening test for the detection of malignant metastatic compression fractures. In old age, a high titer of CRP needs more precise clinical definition for the detection of malignancy in compression fracture.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Coluna Vertebral
/
Proteína C-Reativa
/
Programas de Rastreamento
/
Sensibilidade e Especificidade
/
Dor nas Costas
/
Fraturas por Compressão
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Orthopaedic Association
Ano de publicação:
2003
Tipo de documento:
Artigo
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