Porous Beta-Calcium Pyrophosphate as a Bone Graft Substitute in a Canine Bone Defect Model / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 384-392, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-655962
ABSTRACT
PURPOSE:
To evaluate the possibility of using porous beta-calcium pyrophosphate (beta-CPP) as a bone graft substitute by comparing its osteoconduction and degradation with porous hydroxyapatite (HA). MATERIALS ANDMETHODS:
Porous HA and porous beta-CPP were implanted in the proximal tibia of 7 dogs. Two animals were sacrificed at 8weeks and 5 animals were sacrificed at 20 weeks after surgery. Radiographs and histologic sections were evaluated.RESULTS:
The mean period required for the radiolucent zone to disappear was 7.1+/-1.1 weeks in HA and 6.4+/-1.1 weeks in beta-CPP. By serial radiography, resorption was more prominent in porous beta-CPP than in porous HA at 8 weeks (p=0.04) and at 20 weeks. The proportion of bony tissue in the pore was 16.8% in HA and 29.7% in -CPP. The proportion of pores with bony tissue was 70.2% in HA and 62.5% in beta-CPP at 8 weeks.CONCLUSION:
In beta-CPP, the new bone growth was as vigorous as in HA, but the degradation was more rapid than in HA. These results suggest that beta-CPP is a more ideal new bone graft substitute.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tíbia
/
Desenvolvimento Ósseo
/
Regeneração Óssea
/
Radiografia
/
Durapatita
/
Transplantes
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
Idioma:
Coreano
Revista:
The Journal of the Korean Orthopaedic Association
Ano de publicação:
2003
Tipo de documento:
Artigo
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