The Relationship between Ciliary Beat Frequency and Maxillary Sinus Mucosal Hypertrophy on Computed Tomography in Patients with Chronic Sinusitis / 대한이비인후과학회지

ABSTRACT

BACKGROUND AND OBJECTIVES: This study was designed to investigate the relationship between the sinus mucosal hypertrophy and ciliary beat frequency (CBF) in patients with chronic sinusitis in vitro. MATERIALS AND METHODS: In 14 patients with chronic sinusitis, mucosal samples were obtained from the superior, inferior, and lateral walls of the maxillary sinus. Using a video-computerized analysis technique, we measured two parameters for ciliary activity at five different sites selected randomly from each sample=the ciliated area (%) showing CBF equal to or higher than 10 Hz (A10) and the weighted frequency (Fw). Mucosal hypertrophy of the maxillary sinus was calculated using a computer program on CT scans. RESULTS: A(>or=10) and Fw were 91% and 11.3 Hz in control group, respectively, whereas they were 47% and 9.1 Hz in chronic sinusitis group, respectively (p=0.03). There was a significant inverse correlation between A(>or=10) or Fw and mucosal hypertrophy of the maxillary sinus (p=0.001). CONCLUSION: The results of this study suggest that the severity of mucosal hypertrophy on CT scan may correlate with the ciliary activity.