Synthesis of new Imidazoline derives by the ethylene diamine cyclization from nitril compounds
Journal Ho Chi Minh Medical
;
: 247-252, 2005.
Artigo
em Vietnamita
| WPRIM
| ID: wpr-6568
ABSTRACT
The imidazol and imidazoline derives have many advantages in therapy. For the synthesis of new imidazoline derives, the authors implemented the ethylene diamene cyclization from nitril compounds differently substituted. Then, a dehydrogenation of these imidazolines leaded to the imidazol derives. The last reaction consisted of the condensation of these imidazolines and imidazoles. The authors subjected their synthesized products to an ophthalmic protective evaluation (anti-oedema, secondary anti-hyperemia) on the experimental ocular irritancy models
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ciclização
/
Imidazolinas
Idioma:
Vietnamita
Revista:
Journal Ho Chi Minh Medical
Ano de publicação:
2005
Tipo de documento:
Artigo
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