Endothelial Dysfunction in Patients with Exaggerated Blood Pressure Response during Exercise Test
Korean Circulation Journal
;
: 498-504, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-65743
ABSTRACT
BACKGROUND AND OBJECTIVES:
The diagnostic and prognostic importance of exaggerated blood pressure response to exercise is controversial. Endothelial dysfunction has been demonstrated in patients with atherosclerosis and risk factors for coronary artery disease, but there is a lack of information in patients with exercise hypertension. Thus, we designed this study to evaluate the endothelial function in patients with exaggerated blood pressure response during exercise. SUBJECTS ANDMETHODS:
Exercise hypertension is defined as a systolic blood pressure >or= 210 mmHg in men, and >or=190 mmHg in female, during Treadmill tests. Using a high resolution ultrasound technique, the endothelial function of the brachial artery, in patients with exercise hypertension (n=25), and control subjects (n=25), were investigated.RESULTS:
Endothelial-dependent vasodilation were impaired in patients with exercise hypertension (7.77+/-5.14 vs. 2.81+/-2.29%, p<0.05). On univariate analysis, the extent of vasodilation was significantly correlated with age (r=0.43, p<0.05) and systolic blood pressure (r=0.39, p<0.05).CONCLUSION:
We conclude that patients with exercise hypertension have impaired endothelium-dependent vasodilation. Exercise hypertension is a finding, which may, by itself, raise concern when interpreted as an exercise test. This study also supports the concept that endothelial dysfunction may play a role in exercise hypertension.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vasodilatação
/
Pressão Sanguínea
/
Doença da Artéria Coronariana
/
Artéria Braquial
/
Fatores de Risco
/
Ultrassonografia
/
Endotélio
/
Aterosclerose
/
Teste de Esforço
/
Hipertensão
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Circulation Journal
Ano de publicação:
2002
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS