Analysis the changes of blood biochemical indexes in patients with severe burn / 国际检验医学杂志

ABSTRACT

Objective To investigate the changes of blood biochemical indexes in patients with severe burn ,so as to improve the reference of clinical treatment plan .Methods Totally 152 patients with severe burn treated in the hospital from February 2012 to October 2016 were selected as the observation group ,the blood coagulation indexes of APTA ,PT ,TT ,INR ,FBg ,PLT ,and ALB , AST ,ALT ,TP ,NO ,ESR ,blood CO2 ,UA ,HDL-C ,CHOL ,RBC ,HGB and HCT blood index were measured ;and 92 cases of mild and moderate burn patients were selected as control group ,the similar indexes of two groups were compared .Results The heart rate ,respiratory rate ,diastolic blood pressure and systolic blood pressure in the severe burn group were significantly higher than those in the control group(P< 0 .05) .The levels of APTT ,PT ,TT ,INR ,FBg and PLT in severe burn group were significantly higher than those in control group(P<0 .05) .The levels of AST ,ALT and NO in severe burn group were significantly higher than those in the control group (P<0 .05);the levels of ALB ,TP ,CO2 ,UA ,HDL-C ,CHOL ,HGB ,RBC and HCT were significantly lower than those of the control group(P<0 .05) .Conclusion Through the detection of severe burn patients with some blood inde-xes ,according to changes in coagulation indexes and biochemical indicators to determine the characteristics of the patient′s injury ,assist doctors in the diagnosis and treatment of patients ,could be timely rehydration ,nutritional support ,improve coagulation status ,improve pa-tient immunity .