Clinical Study on Yiqi Qufeng Formula for Treatment of Cough Variant Asthma / 中国中医药信息杂志

ABSTRACT

Objective To discuss the clinical efficacy of Yiqi Qufeng Formula for the treatment of cough variant asthma. Methods Totally 90 cases of cough variant asthma were divided into treatment group and control group through random number table method,with 45 cases in each group.Treatment group was given Yiqi Qufeng Formula, one dose per day, twice a day, orally; while control group was given montelukast sodium tablets, once a day, every night, orally. The treatment for both groups lasted for 4 weeks. Changes in the cough scores, the LCQ total scores, and the recurrence of cough were observed. Results The total effective rate was 93.33% (42/45) in the treatment group and 75.56% (34/45) in the control group, and the treatment group was better than the control group (P<0.05). Compared with before treatment, cough scores decreased in both groups, with treatment group lower than the control group (P<0.05). Compared with before treatment, LCQ total scores in both groups increased, with treatment group higher than the control group (P<0.05). The recurrence rate of cough was 14.29% (6/42) for the treatment group and 52.94% (18/34) for the control group, with statistical significance (P<0.05). Conclusion Yiqi Qufeng Formula has obvious efficacy for treatment of cough variant asthma, which can effectively relieve the cough symptom, reduce the chance of recurrence and improve life quality of patients.