Comparative study on the effects of different concentrations of Iopromide Injection on liver tissue imaging and adverse reactions / 中国生化药物杂志

ABSTRACT

Objective To investigate the effects of different concentrations of iopromide injection on liver tissue imaging and adverse reactions. Methods Selected 150 patients of liver without substantial disease patients, were randomly divided into A group (n=50) and B group (n=50) and C group (n=50), after the abdominal plain, Iopromide Injection injection enhanced scan of the abdominal aorta, portal vein, 5 hepatic tissue, strengthen the evaluation value and the adverse reactions were observed, compared with different concentrations of Iopromide Injection imaging effect and adverse reaction of liver tissue. Results A group was injected with 370 mg/mL Iopromide Injection after abdominal aorta was 249.21, the enhancement of portal vein was 132, B group were injected with 350 mg/mL value of 229.32 Iopromide Injection portal vein enhancement, portal vein enhancement value was 121.32, C group were injected with 300 mg/mL Iopromide Injection hepatic enhancement value was 239.21, the enhancement of portal vein was 98.32, the A group and B group, there was significant difference with C group (P<0.05). There was no significant difference in adverse reactions between the three groups when injected with different concentrations of iopromide injection. Conclusion The results show that the imaging effect is better with the increase of concentration, and there is no significant difference between the patients with high concentration contrast agent and low concentration contrast agent.