Comparison on clinical features between dilated cardiomyopathy patients with or without right heart failure / 中国生化药物杂志

ABSTRACT

Objective To compared the clinical data of dilated cardiomyopathy (DCM) patients who were only left or right heart failure with the DCM patients who were right heart failure as the main clinical manifestations. Methods During January 2013 to January 2017, 25 cases of DCM with right heart failure as the main clinical manifestations, 55 cases of DCM with only left heart failure and 10 cases of DCM with only right heart failure were admitted in our department. The demographic and clinical data, echocardiography, brain natriuretic peptide(BNP) and serum total bilirubin were analyzed. Results Sex, age, course of disease and vital signs were similar between the three groups, while the left ventricular end diastolic diamesion[(76.3±13.7)mm,(67.6±12.3)mm, (59.4±4.2)mm], dimension of the left atrium[(58.5±9.3)mm, (47.4±7.2)mm, (49.0±6.5) mm], pulmonary artery pressure[(55.2±12.4)mmHg, (37.8±7.7)mmHg, (35.9±7.1)mmHg], incidence of pericardial effusion(9/25, 6/55, 1/10), BNP level[(1378.3±441.6)ng/mL, (897.2±353.4)ng/mL (766.4±381.7)ng/mL] were significantly higher while left ventricular ejection fraction(LVEF) was significantly lower in DCM with right heart failure as the main clinical manifestations than those in DCM with only left or right heart failure[(44.6±28.3)μmol/L, (20.1±11.7) μmol/L,P<0.05]. Conclusion DCM patients with right heart failure as the main clinical manifestations is linked with worse clinical features than DCM patients with only left or right heart failure.