Clinical and pathological analysis of periorbital pilomatricoma in 46 children / 眼科新进展

ABSTRACT

Objective To analyze the clinical and pathological features of chil dren's periorbital pilomatricoma.Methods The clinical and pathological data of 46 children patients who were diagnosed as periorbital pilomatricoma and underwent surgical treatment between February 2012 and February 2017 were analyzed.Results Of the 46 patients,18 males and 28 females (malefemale =l.001.56),lesion location of superciliary arch was observed in 26 patients (56.5％),upper eyelid was in 18 patients(39.1％),and the lower eyelid in 2 patients(4.3％).Light microscope was used for pathological examination and the results showed that pilomatricoma was composed of two major cells,and they were basaloid cells and shadow cells.There were 36 patients presenting calcification,25 patients with inflammatory cell infiltration,and 24 patients with multinucleated giant cells.Furthermore,no recurrence or malignant transformation occurred in these patients after surgery.Conclusion Pilomatrixoma presents typical clinical and pathological feature,and it is not uncommon for children patients with periorbital pilomatricoma,so the clinical characteristics of the pilomatricoma and differential diagnosis of the periorbital tumors is important to improve the diagnostic accuracy.