Survey of cognitive dysfunction and influencing factors in elderly inpatients in geriatric department of general hospital / 中华老年医学杂志

ABSTRACT

Objective To investigate the cognitive dysfunction of inpatients in geriatric department general hospital and to analyze the influencing factors.Methods A total of 205 patients hospitalized in Peking University Third Hospital were evaluated by mini-mental state examination (MMSE).All patients were divided into cognitive impairment group and non cognitive impairment group.The general characteristics,prevalence,biochemistry indexes,comorbidities,and color ultrasound-detected plaque and stenosis in carotid arteries and artery of lower extremity were analyzed and compared between two groups.The logistic multiple regression analysis was used to explore the influencing factors of cognitive dysfunction.Results The differences in age(P=0.027),education (P =0.003),marital status(P=0.000),living situation(P=0.001),hypertension history(P =0.031),type 2 diabetes mellitus (T2DM) history (P =0.036),cerebrovascular disease history (P 0.043)and HbA1c(P=0.032)were statistically significant between cognitive impairment and non cognitive impairment group (all P＜ 0.05).Logistic multiple regression analysis showed that age,marital status,T2DM history,cerebrovascular disease history and comorbidities were positively correlated with cognitive impairment(all P＜0.05).Education was negatively correlated with cognitive impairment(P＜0.05).Conclusions Cognitive impairment is associated with age,education,marital status,T2DM history,cerebrovascular disease history and comorbidities.