Analysis of risk factors for high risk ventricular arrhythmias after emergency PCI / 心血管康复医学杂志

ABSTRACT

Objective:To explore risk factors for high risk ventricular arrhythmias (HRVA)after emergency percuta-neous coronary intervention (PCI)in patients with ST elevation acute myocardial infarction (STEMI).Methods:The clinical data of 176 STEMI patients undergoing PCI were retrospectively analyzed.According to presence or not of HRVA after PCI,they were divided into HRVA group (n=34)and no HRVA group (n=142).Single factor and multifactor Logistic regression analysis were used to analyze risk factors for HRVA.Results:Compared with no HRVA group,there were significant rise in levels of serum creatinine [SCr,(86.43±21.26)mmol/L vs.(96.67± 20.85)mmol/L],glycosylated hemoglobin A1 [HbA1c,(6.13 ± 1.53)% vs.(6.75 ±0.74)%],white blood cell count [(10.09±3.34)109/L vs.(11.73±3.42)109/L]and percentage of Killip class VI (2.94% vs.14.7%),and significant reduction in level of low density lipoprotein cholesterol [(3.16±0.92)mmol/L vs.(2.75±0.87)mmol/L]in HRVA group,P <0.05 or <0.01;multifactor Logistic regression analysis indicated that HbA1c,white blood cell count,cardiac function Killip class and SCr were independent risk factors for HRVA after PCI in STEMI pa-tients (OR=4.012~7.145,P <0.05 or <0.01).Conclusion:Glycosylated hemoglobin A1,white blood cell count, cardiac function grading and creatinine are closely correlated with occurrence of HRVA after emergency PCI in STEMI patients.Timely treatment can reduce occurrence of HRVA.