Clinical Effects of Buzhong Yiqi Wuling Decoction Combined Carvedilol in the Patients with Chornic Heart Failure / 中国药师

ABSTRACT

Objective:To discuss the clinical effects of Buzhong Yiqi Wuling decoction combined with carvedilol in the patients with chornic heart failure. Methods:Totally 68 patients with chornic heart failure from June 2014 to January 2016 in our hospital were randomly selected and divided into the control group with 34 patients treated with carvedilol and the research group with the other 34 patients treated with Buzhong Yiqi Wuling decoction combined with carvedilol. The TCM symptom integral, distances of 6-minute walk-ing test, NT-ProBNP plasma levels, LVEF, LVEDD and LVESD before and after the treatment in the two groups were compared, and the clinical symptoms, cardiac function and adverse reactions in the two groups were observed to evaluate the clinical effects. Results:The TCM symptom integral and NT-ProBNP levels in the research group after the treatment were lower than those in the control group, and the distances of 6-minute walking test in the research group after the treatment was longer than that in the control group, the LVEF in the research group after the treatment was higher than that in the control group, the LVEDD and LVESD in the research group after the treatment were smaller than those in the control group, and all the differences were statistically significance(P<0. 05). The total effective rate was 91. 2% in the research group, which was higher than that in the control group (70. 6%), and the difference was sta-tistically significance(P<0. 05). No difference in the incidence of adverse reactions was shown between the groups (P>0. 05). Con-clusionBuzhong Yiqi Wuling decoction combined with carvedilol in the patients with chornic heart failure can improve the clinical symptoms, cardiac function and exercise tolerance with fewer adverse reactions, which is worthy of clinical use.