Clinical effect of Danhong injection combined with acupuncture in the treatment of vascular parkinson / 国际中医中药杂志

ABSTRACT

Objective To study the clinical effect of Danhong injection combined with acupuncture in the treatment of vascular Parkinson syndrome (VP). Methods A total of 98 patients with VP who were treated in the hospital from January 2015 to January 2017 were enrolled in this study. According to the digital random table method, the patients were divided into two groups, the observation group and the control group with each 49 cases. Both groups were given basic treatment, and based on that, the observation group was treated with Danhong injection and acupuncture treatment. Both groups were compared before and after 8 weeks of treatment with the outcome indices of exercise and motor function score, blood rheology index and cerebral hemodynamic indexes, as well as adverse reactions. Results The total effective rate of the observation group was 87.76% (43/49), while the control group was 71.43% (35/49), and the difference was statistically significant(χ 2=4.021,P<0.05).After treatment,the motor function score(27.4 ± 10.5 vs.32.8 ± 8.2,t=2.865), the scores of non-motor function(4.1 ± 2.2 vs.9.8 ± 4.0,t=8.785)of the observation group were lower than those of the control group(P<0.05).After treatment,the plasma viscosity(1.49 ± 0.21 mPa?s vs.1.64 ± 0.28 mPa?s,t=3.000),fibrinogen(3.18 ±0.77 g/L,vs.3.86 ±0.70 g/L,t=4.574),and the RI index(0.49 ±0.12 vs. 0.62 ± 0.16, t=4.550) of the observation group was significantly lower than those of the control group (P<0.05). The Vs(81.97 ± 12.65 cm/s vs.74.39 ± 9.48 cm/s,t=3.357) and Vm(61.54 ± 7.10 cm/s vs.55.87 ± 6.24 cm/s,t=4.199) of observation group was significantly higher than those of the control group(P<0.05). The total incidence of adverse reactions in the observation group was 14.29%, which was no significant difference compared with that of the control group of 16.33%(χ 2=0.079,P>0.05).Conclusions The Danhong injection combined with acupuncture showed better effect on VP patients, and it could improve the clinical symptoms and blood circulation.