Vitamin D insufficiency is associated with food sensitization in children under 2 years with atopic dermatitis
Allergy, Asthma & Respiratory Disease
;
: 211-215, 2013.
Artigo
em Coreano
| WPRIM
| ID: wpr-66336
ABSTRACT
PURPOSE:
Vitamin D levels are known to be associated with development of allergic diseases. However, existing data are controversial. The aim of this study was to investigate whether vitamin D levels are associated with food sensitization (FS) in young children with atopic dermatitis (AD).METHODS:
We performed a medical record review of all patients under 2 years presenting to pediatric allergic clinic in Hallym University Sacred Heart Hospital for atopic dermatitis between March 1, 2012 and February 28, 2013. Serum 25-hydroxyvitamin D (25(OH)D)levels and six specific immunoglobulin E (IgE) to common food allergens were measured in 132 young children with AD. We defined vitamin D insufficiency was 25(OH)D or =0.35 IU/mL to any of six common food allergens. Associations between serum 25(OH)D levels and FS were examined by using multiple logistic regression, adjusting for potential risk and confounding factors.RESULTS:
The mean age was 10.1 months. Among the 132 children with AD, 65.9% had FS. In this group, there was a negative correlation between 25(OH)D levels and serum eosinophil percentage (correlation coefficient [r]=-0.335, P<0.01), but not correlated with serum total IgE levels. Children with vitamin D insufficiency were more likely to have FS (adjusted odds ratio, 17.1; 95% confidence interval, 1.36 to 215; P=0.028) than those with adequate vitamin D levels.CONCLUSION:
Vitamin D insufficiency is associated with FS in young children with AD. Further research is needed to confirm these findings.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vitamina D
/
Vitaminas
/
Imunoglobulina E
/
Imunoglobulinas
/
Alérgenos
/
Modelos Logísticos
/
Razão de Chances
/
Prontuários Médicos
/
Dermatite
/
Dermatite Atópica
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Criança
/
Humanos
Idioma:
Coreano
Revista:
Allergy, Asthma & Respiratory Disease
Ano de publicação:
2013
Tipo de documento:
Artigo
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