Research progress of three long-acting basic insulin analogues / 药物评价研究
Drug Evaluation Research
;
(6): 1671-1676, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-664606
ABSTRACT
Diabetes is a kind of worldwide chronic disease with high incidence,which threatens people's lives and work.With the development of DNA recombination technology,long-acting basal insulin analogues bring gospel and hope for patients with diabetes.Insulin glargine (IGla),detemir (IDet) and degludec (IDeg),as three basic types of insulin,commonly used in clinical practice that slowly absorbed and distributed by changing the structure,and relatively long acting time,more fit the physiological model of insulin secretion.Therefore,the existing studies of molecular structure,long-acting mechanism,safety evaluation and pharmacodynamic effects of three kinds of insulin preparations are briefly summarized.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Drug Evaluation Research
Ano de publicação:
2017
Tipo de documento:
Artigo
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