Analysis of risk factors related to revascularization in percutaneous coronary intervention elderly / 中国介入心脏病学杂志

ABSTRACT

Objective To analyze the risk factors of repeat revascularization after percutaneous coronary intervention (PCI) in elderly patients.Methods A total of 315 patients,aged 60-99 (72.89±7.80) years hospitalized during 2004 and 2015 due to coronary heart disease and received PCI therapy in the geriatric department of Peking University First Hospital were enrolled.Patients who received repeat revascularization were divided into the target lesion repeat revascularization (TLR)group and the non target lesion revascularization (non-TLR)group.Multivariate regression analysis was performed to make comparisons with non repeat revascularization group respectively and evaluate related risk factors.The median follow-up was 62months.Results The rate of TLR was less than non-TLR in elderly patients.Multivariate regression analysis showed that diabetes mellitus (HR 4.56,95％ CI 1.94-10.75,P＜0.05) and number of stents (HR 1.55,95％ CI 1.05-2.29,P＜0.05) were related risk factor of TLR,while age (HR 0.94,95％ CI 0.90-0.98,P＜0.05),the value of LDL-C reduction (HR 2.51,95％ CI 1.56-3.99,P＜0.05),the proportion of bifurcation lesions (HR 2.24,95％ CI 1.20-4.17,P＜0.05) and residual SYNTAX score (rSS) (HR 1.07,CI95％ 1.02-1.11,P＜0.05) wererelated risk factors of non-TLI.Conclusions The incidence of non-TLR were higher than TLR in elderly patients.Increased total number of stent implantation and diabetes mellitus were related risk factors of TLR,while the lower average age,less reduction of LDL-C,increased proportion of bifurcation lesions and higher rSS were related risk factors of non-TLR.