Comparison of ultrasonic manifestations among triple-negative breast cancer and BI-RADS 4A atypical fibroadenoma or adenosis / 中国医学影像技术

ABSTRACT

Objective To compare ultrasonic manifestations of triple-negative breast cancer (TNBC),BI-RADS category 4A atypical fibroadenoma and adenosis.Methods Ultrasonic findings of TNBC group (n=42),BI-RADS 4A atypical fibroadenoma group (n=34) and adenosis group (n =36) were analyzed retrospectively,and statistical analysis was performed.Results There were statistically significant differences of age,tumor size,shape,echo,margin and BI-RADS category between TNBC group and fibroadenoma group (all P＜0.016 7).There were statistically significant differences (all P＜0.016 7) of age,size,margin,peripheral duct changes,and BI-RADS category between TNBC group and adenosis group.There were statistically significant differences of shape between fibroadenoma group and adenosis group (P＜0.016 7).There was no statistically significant difference of boundary,halo,posterior acoustic features,orientation,nor calcification among three groups (all P＞0.05).Conclusion TNBC often occurs in women older than 50 years old,and the lesions usually demonstrate larger than 2 cm,very lower echo,and irregular shape with distinct margin.TNBC is usually associated with harder elastography feature,and is classified as more than BI-RADS 4B.Fibroadenoma classified as BI-RADS 4A is most likely to be a mass with lobulated or irregular shape with distinct margin.Adenosis classified as BI-RADS 4A often appears irregular and vertical orientation,which may be confused with breast cancer.