Therapeutic effect of noninvasive positive pressure ventilation on arrhythmia in patients with CHD complicated OSAHS / 心血管康复医学杂志

ABSTRACT

Objective:To explore therapeutic effect of noninvasive positive pressure ventilation(NPPV)on arrhythmi-a in patients with coronary heart disease(CHD)complicated obstructive sleep apnea-hypopnea syndrome(OSAHS). Methods:A total of 90 CHD + OSAHS patients were selected from our hospital.They were randomly and equally divided into routine treatment group and NPPV group(received NPPV treatment based on routine treatment).After three-month treatment,incidence of supraventricular arrhythmias,ventricular arrhythmias and adverse cardiovascu-lar events were compared between two groups.Results:Compared with routine treatment group after three-month treatment,there were significant reductions in times of supraventricular arrhythmia[(659.3 ± 15.6)times/8h vs.(124.9 ± 12.6)times/8h],ventricular arrhythmia[(298.3 ± 15.3)times/8h vs.(79.6 ± 10.2)times/8h],prema-ture ventricular contraction[(3927 ± 709)times/d vs.(2524 ± 418)times/d]and nonsustained ventricular tachycar-dia[(4.91 ± 2.34)times/d vs.(1.12 ± 0.83)times/d]in NPPV group,P=0.001 all;incidence rate of adverse car-diovascular events in NPPV group was significantly lower than that of routine treatment group(2.2% vs.17.8%,P=0.035).Conclusion:Noninvasive positive pressure ventilation can reduce incidence of arrhythmias and adverse cardiovascular events in patients with coronary heart disease complicated obstructive sleep apnea-hypopnea syn-drome.