Characteristic analysis of fundus fluorescein angiography and optical coherence tomography findings in uveitis / 上海交通大学学报（医学版）

ABSTRACT

Objective·To investigate the characteristics of fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) findings of patients with uveitis. Methods·The clinical data of 84 patients (135 eyes) diagnosed as uveitis in Renji Hospital, Shanghai Jiao Tong University School of Medicine from Apr 2015 to Aug 2017 were studied retrospectively. FFA and OCT examinations were performed. Results·Of 84 patients, the average age was (44±10) years old. There were more males than females. Fifty-one patients (102 eyes) were affected bilaterally, and 33 patients (33 eyes) were affected unilaterally. Optic fluorescence leakage was found in 73％ of patients, and retinal vascular wall staining was found in 50％ of patients by FFA. Cystoid macular edema was found in 23％ of patients, and neuroepithelial detachment was found in 21％ of patients by OCT. The proportion of common positive manifestation by OCT (10％–40％) was lower than that by FFA (23％–100％) (χ2=33.8, P=0.000). Conclusion·The uveitis usually occurs in young and middle-aged male patients. The most common features of the uveitis patients are optic fluorescence leakage and retinal vascular wall staining by FFA, and cystoid macular edema and neuroepithelial detachment by OCT.