Clinical application of pulmonary embolism risk stratification with multiple markers / 实用医学杂志

ABSTRACT

Objective To evaluate the clinical value of coagulation markers(D-dimer,etc.),myocardial injury markers and blood gas analysis in the risk stratification of PE and prognosis of pulmonary embolism(PE) Methods Totally 201 patients with PE were divided into high-risk group(n=52),intermediate-risk group(n=88),low-risk group(n=61),treatment group(n=67)and 38 normal controls and the level of multiple markers was analyzed. Results DD,Fib,NT-proBNP,PT and PO2of PE patients(high-,intermediate- and low-risk group)were statistically different from those of treatment group and normal controls(P<0.05);cTnⅠ,CK-MB, INR,PTA and RI of high- and intermediate-risk group were statistically different(P < 0.05);but CK and SpO2 were not(P>0.05).Conclusions Multiple markers can be used as a clue to screen high-,intermediate-and low-risk PE.It also could be used to distinguish the prognosis of PE.