Dexamethasone in the prophylaxis of radiation-induced pain deterioration after pallia-tive radiotherapy for bone metastases from lung cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 1194-1198, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-665433
ABSTRACT
Objective:
To evaluate the efficacy and safety of dexamethasone in alleviating radiation-induced pain deterioration follow-ing palliative radiotherapy in patients with bone metastases from lung cancer.Methods:
A total of 103 patients with bone metastases from lung cancer were randomly assigned into the observation group (n=51) and the control group (n=52). Dexamethasone (5 mg, iv) or placebo (saline, 1 mL) was administered after radiation. The incidence of pain deterionation in the two groups was compared. Re-sultsOf the 51 cases in observation group, 13 (25%) had pain deterioration. While 20 patients (38%) experienced aggravated pain in the control group (P=0.03).Conclusion:
Dexamethasone alleviated pain deterioration in patients with bone metastases from lung can-cer following palliative radiotherapy, which needs to be confirmed by further studies.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Chinês
Revista:
Chinese Journal of Clinical Oncology
Ano de publicação:
2017
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS