Impact of iron deficiency anemia on chronic periodontitis and superoxide dismutase activity: a cross-sectional study
Journal of Periodontal & Implant Science
; : 57-64, 2014.
Article
em En
| WPRIM
| ID: wpr-66595
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: Both chronic periodontitis (CP) and iron deficiency anemia (IDA) induce oxidative stress in the body and cause an imbalance between reactive oxygen species and antioxidants, such as superoxide dismutase (SOD). This study explored the SOD enzyme activity of saliva and serum in CP patients with and without IDA and analyzed the impact of IDA on CP. METHODS: A total of 82 patients were divided into four groups: control group (CG, 22), periodontally healthy IDA patients (IDA-PH, 20), CP patients (CP, 20), and IDA patients with CP (IDA-CP, 20). After clinical measurements and samplings, serum and salivary SOD levels were determined using an SOD assay kit. RESULTS: IDA-CP patients exhibited a higher gingival index, bleeding on probing, probing pocket depth, and percentage (%) of sites with a clinical attachment loss (CAL) of > or =6 mm (P or =6 mm (P0.05) in these patients. CONCLUSIONS: Within the limits of this study, it may be suggested that IDA patients with chronic periodontitis have more periodontal breakdowns than patients with chronic periodontitis. Serum and salivary SOD activity levels were lower in the IDA-PH, CP and IDA-CP groups than in the CG. Iron deficiency anemia influenced the serum SOD activity but did not seem to affect the salivary SOD activity in these patients.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Saliva
/
Superóxido Dismutase
/
Índice Periodontal
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Estudos Transversais
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Espécies Reativas de Oxigênio
/
Superóxidos
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Estresse Oxidativo
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Anemia Ferropriva
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Periodontite Crônica
/
Hemorragia
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Journal of Periodontal & Implant Science
Ano de publicação:
2014
Tipo de documento:
Article