The correlation between spleen SWV and portal vein pressure: its application in evaluating the short-term effect of interventional therapy for Budd-Chiari syndrome / 介入放射学杂志

ABSTRACT

Objective To discuss the application of the correlation between spleen shear wave velocity (SWV) and portal vein pressure in evaluating short-term curative effect of interventional therapy for Budd-Chiari syndrome (BCS).Methods The clinical data of a total of 30 BCS patients,who were admitted to authors' hospital during the period from May 2016 to October 2016 to receive treatment,were collected.The hepatic venous pressure gradient (HVPG) was measured before as well as after percutaneous transluminal angioplasty in all patients.Spleen SWV,the velocity and internal diameter as well as the velocity-to-diameter ratio of portal vein were calculated,the results were statistically analyzed.Results Technical success was achieved in all 30 patients.The mean HVPG score was strikingly reduced from preoperative (13.70±4.55)mmHg to postoperative (3.20±1.94) mmHg (P＜0.05).The preoperative and postoperative difference in HVPG had a parallel relationship with the preoperative and 2-day postoperative difference in spleen SWV as well as with the preoperative and 2-day postoperative difference in velocity-to-diameter ratio (r=0.856,P＜0.0001 and r=0.741,P＜0.0001 respectively).Conclusion A significant correlation exists between the spleen SWV and HVPG,therefore,SWV can be used as an effective index to evaluate the short-term curative effect of interventional treatment for BCS.