The relationship between DNA methylation profile of peripheral blood and smoking / 中国法医学杂志
Chinese Journal of Forensic Medicine
;
(6): 508-511, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-666525
ABSTRACT
Objective To evaluate the potential application of separating smoking individuals from non-smoking ones by DNA methylation profiles from peripheral blood. Methods Human genome-wide DNA methylation data were downloaded from NIH GEOdata base. DNA methylation values from certain CpG sites were used to evaluate their significance between smokers and non-smokers by Student's T Test, as well as the clustering analysis. Results There are significant DNA methylation between smokers and non-smokers for certain CpGs. Conclusion Detection of methylation status from human peripheral blood can distinguish smokers from non-smokers.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Forensic Medicine
Ano de publicação:
2017
Tipo de documento:
Artigo
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