Review of thepathogenesis of chronic uric acid nephropathy / 中国糖尿病杂志
Chinese Journal of Diabetes
;
(12): 950-952, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-666905
ABSTRACT
Hyperuricemia is the result of purine metabolic or excretion disorder.Continuous hyperuricemia can cause chronic uric acid nephropathy (gouty nephropathy),which will induce varying degrees of renal disfunction and impair life.Uric acid contributes to kidney injury by inducing inflammation,endothelial dysfunction,oxidative stress,and activation of the renin-angiotensin system(RAS),and cause chronic uric acid nephropathy.Thorough tnderstanding of.the pathogenesis of chronic uric acid nephropathy is beneficial for dru development and evaluating disease prognosis.Here,we reviewed of the pathogenesis of chronic uric acid nephropathy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Diabetes
Ano de publicação:
2017
Tipo de documento:
Artigo
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