Research Progress of PLA2R and anti-PLA2R Antibodies in Membranous Nephropathy / 现代检验医学杂志

ABSTRACT

In recent years,the phospholipase A2 receptor in membranous nephropathy as an antigen has been confirmed,people have a new understanding of the mechanism of membranous nephropathy.Abundant clinical trials showed anti-PLA2R antibody in membranous nephropathy formed the important pathogenic mechanism,and it's related to disease activity,result and prognosis,it can also predict the process of disease remission,even can help make treatments for patients.This paper gathered some progress locally and abroad to describe the anti-PLA2R antibody's in function membranous nephropathy.