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Research advances in the relationship between PARP-1 and its inhibitors and the development, progression,and radiosensitivity of tumors / 中华放射肿瘤学杂志
Chinese Journal of Radiation Oncology ; (6): 1350-1353, 2017.
Artigo em Chinês | WPRIM | ID: wpr-667546
ABSTRACT
Poly(ADP-ribose)polymerase-1(PARP-1),a ubiquitous and abundant nuclear protein composed of amino-acid residues, plays an important role in the process of DNA damage repair. In recent years,some studies have confirmed that PARP-1 is closely related to the development and progression of tumors,and may influence the tumor radiosensitivity.This article summarizes the relationship of PARP-1 and its inhibitors and the development,progression,and radiosensitivity of tumors.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Radiation Oncology Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Radiation Oncology Ano de publicação: 2017 Tipo de documento: Artigo