Update in the etiology and treatment of sexual precocity / 소아과
Korean Journal of Pediatrics
;
: 718-725, 2006.
Artigo
em Coreano
| WPRIM
| ID: wpr-66799
ABSTRACT
The pubertal activation of gonadotrophin releasing hormone(GnRH) requires coordinated changes in excitatory or inhibitory amino acids, growth factors, and a group of transcriptional regulators. The age of onset of puberty is progressing to younger age. Factors affecting early puberty include genetic traits, nutrition(body fat) and exposure to endocrine disrupting chemicals. In rapidly progressing central precocious puberty, gonadotrophin releasing hormone(GnRH) agonists(GnRHa) appear to increase final height if treated early stage. Further large scaled long-term follow-up study of the effects of GnRHa on final height is needed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Puberdade Precoce
/
Puberdade
/
Idade de Início
/
Peptídeos e Proteínas de Sinalização Intercelular
/
Disruptores Endócrinos
/
Aminoácidos
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2006
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS