Effect of intraoperative hypothermia therapy on immune function and recovery of neurological function in elderly patients with acute intestinal obstruction during perioperative period / 中国基层医药

ABSTRACT

Objective To investigate the effect of intraoperative hypothermia therapy on immune function and neurological function recovery in elderly patients with acute intestinal obstruction.Methods 80 elderly patients with acute intestinal obstruction were selected,and they were randomly divided into two groups according to the digital table,40 cases in each group.The control group was treated with conventional symptomatic support.The observation group was treated with intraoperative hypothermia therapy.The CD4+,CD8+,CD4+/CD8+ and the levels of ESS and Barthel index in the two groups after intervention were observed.Results The levels of CD4+,CD8+ in the observation group were higher than those in the control group(t =26.242,23.908,all P ＜0.05),CD4+/CD8+ was lower than that in the control group(t =5.262,P ＜0.05).The levels of IgM,IgG and IgA in the observation group were higher than those in the control group (t =52.623,28.342,53.126,all P ＜0.05).The ESS and Barthel index of the observation group were higher than those of the control group (t =11.486,10.902,all P ＜ 0.05).Conclusion Mild hypothermia can reduce the immune function of elderly patients with acute intestinal obstruction,promote the recovery of nervous system and improve the postoperative quality of life.