Frequency and Associated Factors of Generalized Bone Loss in Premenopausal Early Rheumatoid Arthritis / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 50-57, 2002.
Artigo
em Coreano
| WPRIM
| ID: wpr-66826
ABSTRACT
OBJECTIVE:
To investigate frequency and associated factors of generalized bone loss in patients with premeonpausal early rheumatoid arthritis (RA)who had not been treated with corticosteroid.METHODS:
We measured bone mineral density (BMD)of lumbar spine and hip by dual energy X-ray absorptiometry (DEXA,Hologic QDR 4500)and investigated clinical;age,disease duration,numbers of tender and swollen joint,and laboratory;erythrocyte sedimentation rate (ESR),C-reactive protein (CRP)and rheumatoid factor (RF),variables in patients with premenopausal early RA who had not been treated with corticosteroid,consecutively.Generalized bone loss was defined as T score less than -1,and clinical and laboratory variables were analyzed for generalized bone loss.RESULTS:
In 41 patients with premenopausal early RA (age;38 +/-8 years, duration of disease 8 +/-6 months),the frequency of generalized bone loss in lumbar spine and hip were 35%and 46%.In multivariate logistic regression analysis,elevated CRP level was significantly associated with generalized bone loss in lumbar spine and femur neck.CONCLUSIONS:
In patients with premenopausal early RA,elevated CRP level was associated with generalized bone loss of lumbar spine and femur neck.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artrite Reumatoide
/
Fator Reumatoide
/
Coluna Vertebral
/
Absorciometria de Fóton
/
Densidade Óssea
/
Modelos Logísticos
/
Pré-Menopausa
/
Colo do Fêmur
/
Quadril
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Rheumatism Association
Ano de publicação:
2002
Tipo de documento:
Artigo
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