Relationship between sarcopenia and the incidence of fall in elderly-a systematic review of advanced nutritional and physical interventions studies / 中华临床营养杂志

ABSTRACT

Objective To evaluate the relationship between sarcopenia and the incidence of fall in elderly,with a systematic review of advanced nutritional and physical interventions studies.Methods A systematic review of randomized controlled trails (RCTs) and cohort studies was conducted.All published literature related to the sarcopenia,falls,and nutritional,physical interventions in the elderly were searched both in Chinese and English databases including Wanfang Database,CBM/SinoMed,PubMed,EMBASE,and Cochrane Library from January 1987 to January 2017 based on the inclusion and exclusion criteria.According to the standard procedure of systematic review,all selected articles were evaluated and graded by two researchers independently by using Jadad scale or Newcastle-Ottawa scale.Results A total of 168 articles were found,of which 11 (4 RCTs and 7 cohort studies) met the inclusion criteria.It was found that sarcopenia was an independent risk factor for fall among the elderly.Early prevention,accurate identification,and timely nutrition and physical interventions on the sarcopenia were the critical factors for reducing the incidence of accidental falls and fractures in the elderly,which helped to greatly reduce the health care expenditures and improve clinical outcomes and the quality of life.Conclusion Elderly should be screened early for sarcopenia,and nutrition and physical interventions should be applied to improve clinical outcomes and reduce health care costs.