Prognostic analysis of carcinoma of duodenal papilla treated by pancreatoduodenectomy / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4): 630-634, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-668573
ABSTRACT
Objective:
To evaluate the prognostic factors for duodenalpapilla carcinoma (DPC)treated by pancreatoduodenectomy (PD).Methods:
Clinicopathological data of 68 patients with duodenalpapilla carcinoma who undergone PD and finally diagnosed by surgery and histopathology from January 2001 to June 2010 were retrospectively analyzed.The patients were followed-up until 2015.Survival analysis was conducted using the Kaplan-Meier survival and Cox proportional hazards model analysis.The difference in survival curves was evaluated with a log-rank test.Results:
The patients were followed-up with a median follow-up of 57 months (ranging from 4 months to 168 months).The univariate analysis showed that increased serum levels of total bilirubin were correlated with a poor prognosis,as well as a senior grade of infiltration depth,lymph node metastases,and TNM stage (P=0.043,0.003,0.004 0.002,respectively).Only increased serum levels of total bilirubin and a senior grade of TNM stage retained their significance when adjustments were made for other known prognostic factors in Cox multivariate analysis (RR=2.031,P=0.031 and RR=2.255,P=0.029).Conclusions:
Increased serum levels of total bilirubin were correlated with a poor prognosis,as well as a senior grade of infiltration depth,lymph node metastases,and TNM stage.Only increased serum levels of total bilirubin and a senior grade of TNM stage can serve as independent prognosis indexes in the evaluation of patients with DPC after PD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Current Advances in General Surgery
Ano de publicação:
2017
Tipo de documento:
Artigo
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