The Clinical Audiological Characteristics of Infants with Human Cytomegalovirus Pneumonia / 听力学及言语疾病杂志

ABSTRACT

Objective To study the audiology characteristics of infants with human cytomegalovirus (HMCV) pneumonia.Methods Auditory brainstem response (ABR) and acoustic impedance test were carried on the following three groups respectively.The CMV(+) group had 115 infants who have been diagnosed with CMV pneumonia.CMV(-) group had 115 infants with pneumonia but did not have CMV infection.The control Group had 115 healthy children during the same period.A comprehensive evaluation of audiological characteristics and follow-up of hearing changes were studied.Results ①The CMV(+) group had 50 ears (21.74％),the CMV(-) group had 34 ears (14.78％),and the healthy group had 17 ears 7.39％ in ABR V wave threshold over 30 dB nHL.②The CMV(+) group had the highest rate of sens0rineural hearing loss(SNHL) compared with the CMV(-) and health control groups.③The percentages of the abnormal conductive hearing loss(CHL) in the CMV(+) group and CMV(-) group were higher than the health control group while there was no obvious difference between the CMV(+) and the CMV(-) groups.④During a 3-year follow-up,3 infants in the CMV(+)group who suffered SHL recovered while all the infants suffered CHL recovered in hearing.Conclusion Infants with CMV pneumonia have a higher rate of SHL,and pneumonia is likely to cause dysfunction of the middle ear,which might lead to CHL.We need to test infants with CMV pneumonia through thorough clinical audiology examinations and a long-term follow-up.