Research Progress in Polyethylene Glycol Modified Chitosan Applied in Biomedical Field / 中国药师

ABSTRACT

Objective:To provide reference for the intensive study on polyethylene glycol modified chitosan. Methods:The relat-ed literatures at home and abroad were looked up and retrieved from 2004 to 2014, and the related contents were summarized. Results:The methods for the preparation of polyethylene glycol modified chitosan were various. Polyethylene glycol modified chitosan could be used as the carrier for nano-drug and gene therapy, the base of temperature-sensitive hydrogel, polymeric prodrug and the repair mate-rial of tissue engineering. Conclusion:Polyethylene glycol modified chitosan can be wildely used in biomedical field. However, the re-lated research is only in vitro. The in vivo studies should be further systematic and intensive.