Determination of Related Substances in Erythromycin Ophthalmic Ointment / 中国药师
China Pharmacist
;
(12): 2168-2170, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-670137
ABSTRACT
Objective:
To establish a method for the determination of related substances in erythromycin ophthalmic ointment.Methods:
The extraction method was established and optimized. An HPLC gradient elution method was used for the determination of related substances in erythromycin ophthalmic ointment.Results:
One step extraction with PBS (pH 7.0) - methanol(1 1) had promising effect. After the method validation, it was proved that the method could be used to determine the related substances in eryth-romycin ophthalmic ointment.Conclusion:
The method established in the paper provides a better analytical extraction and determina-tion method for the quality control of erythromycin ophthalmic ointment.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2015
Tipo de documento:
Artigo
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