HPV infection,overexpression of P53 and Ki-67 protein in oral warts from HIV-positive patients / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-670709
ABSTRACT
Objective:
To detect P53 and Ki-67 protein,human papill om a virus (HPV),cytomegalovirus(CMV) and Epstein-Barr virus(EBV)in the warts of o ral mucosa from HIV-positive patients.Methods:
The expression P53 and Ki-67 protein,HPV,EBV and CMV were detected by immunohistochemistry and PCR in 34 cases of oral mucosa warts from HIV-positve patients,33 cases of oral epithelia dysplasia and 45 cases of oral squamous cell carcinoma.Results:
(1)The expression of P53 and Ki-67 protein in the cases of oral mucosa warts from HIV-positive patients were 23%and 76% re spectively,lower than those in oral suquamous cell carcinoma lesions from non- HIV individuals(62.8% and 97.8% respectively,P0.05).(2)The HPV infection in the warts of oral mucosa from HIV -positive patients was 88.2%,much higher than in oral suquamous cell carcinoma lesions (35.6%) and in dysplastic lesions (9.1%) from non-HIV individuals(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Practical Stomatology
Ano de publicação:
2000
Tipo de documento:
Artigo
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