Experimental study on bioactive membrane for guided bone regeneration in alveolar cleft / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-670711
ABSTRACT
Objective:
To evaluate the effect of barrier m em brane on guided bone regeneration(GBR) in alveolar cleft.Methods:
The alveolar cleft of animal model was established in the maxilla in 10 rabbi ts. The artificial alveolar clefts were treated immediately with following mater ials respectively (1) PLA+collagen+rhBMP-2 membrane, (2)PLA membrane, (3)colla ge membrane, (4) blank control. All the membranes were fixed by PLA pin and mini -titanium pin. The animals were sacrificed 2 weeks, 1,2,3 and 6 months after su rgery respectively. Samples were studied through macroscopic observation, X-rad iography, histomorphology and enzyme histochemistry analysis.Results:
In the clefts covered with the 3 kinds of membrane more bone fromation wa s observed. The compound membrane of PLA+collagen+rhBMP-2 showed the best bone regeneration effects.Conclusion:
The GBR technique can be used to repair the bone defect of alveolar cleft.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Practical Stomatology
Ano de publicação:
2000
Tipo de documento:
Artigo
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